Article
J. Breath Res. 10, 017105 (2016) [DOI: 10.1088/1752-7155/10/1/017105]

Modeling of breath methane concentration profiles during exercise on an ergometer

Anna Szabó, Karl Unterkofler, Pawel Mochalski, Martin Jandacka, Vera Ruzsanyi, Gábor Szabó, Árpád Mohácsi, Susanne Teschl, Gerald Teschl, and Julian King

Abstract
We develop a simple three compartment model based on mass balance equations which quantitatively describes the dynamics of breath methane concentration profiles during exercise on an ergometer. With the help of this model it is possible to estimate the endogenous production rate of methane in the large intestine by measuring breath gas concentrations of methane.

Keywords: Modeling, Breath gas analysis, Methane, Volatile organic compounds (VOCs), Production rates, SRI-PTR-TOF-MS, Exercise

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